That year he was traded to the St. Louis Cardinals for a player to be named later, who turned out to be George Frazier. He hit over .280 in both the 1982 & 1983 seasons. They were both minor league bests for him, while he was playing a fine short stop.
Santana began the 1983 season with the Cardinals & watched the team raise their 1982 World Series Champion flag in the home opener. There he was a team mate of Kieth Hernandez, one of the Cardinals biggest stars.
He would appear in 30 games for the Cardinals, mostly as a defensive replacement & pinch hitter batting just .214. By the end of June he was sent back down to AAA. In January of 1984 he was released by St. Louis & a few hours later signed with the New York Mets.
In 1984 Santana batted .276 at AAA Tidewater in 77 games & was called up to the Mets by July, to fill a roster spot. He started his Mets career as Jose Oquendo’s back short stop eventually taking over the position by August.
The scouting reports on Santana said he had limited range, with good speed and a strong arm. It is now known, that he would drive first baseman Keith Hernandez crazy with his high arched throws that would barely the base runners. It also seemed Santana would only fire the ball when absolutely necessary, otherwise it appeared he lobbed the ball over the infield on a constant basis.
In fifty games at short, he made six errors with a .970 fielding %. In 1984 at the plate he hit .271 with eleven doubles, one triple, & 12 RBIs. He hit the first of his 13 career HRs during the last week of the season in a game against the Philadelphia Phillies.
By 1985 the Mets traded off Oquendo & Santana became the teams regular shortstop, a job he would hold for three seasons. He was a weak hitter and mostly batting in the eighth spot within a strong Mets mid eighties line up of power hitters. He would hit .257 in 1985, which was his career best as a regular player, with one HR, 19 doubles & 29 RBIs. He led all short stops in put outs (301) turned 81 double plays, & made 25 errors (fifth most in the league).
In the 1986 Championship season he hit under .200 most of the season. On May 24th he doubled home two runs in the 4th inning, off the Padres Mark Thurmund. The runs put the Mets ahead in a game they would win 5-4. In June he drove in five runs but was still batting under .200, until he had a good August getting him over that mark.
He began the month with a six game hit streak & on August 15th he had one of his biggest offensive days. He had three hits with a pair of doubles & two runs scored against the St. Louis Cardinals in a 4-2 loss at Shea.
On August 26th he hit ahis only HR of the year, it came off Dave Dravecky & the Padres at Jack Murphy Stadium. In September he actually had three separate multi RBI games as the Mets rolled into the playoffs. Santana finished the season at .218, with one HR 11 doubles 28 RBIs & a .285 on base %. His .973 fielding % was fourth best among NL shortstops.
As a member of a wild bunch on the 1986 team, Santana was a low key type of guy. He never got in any trouble & always conducted himself like a gentleman. In a 2009 interview from his home in Cape Coral, Florida he said: "I never got in trouble. I was never arrested. My job was too important for me to do something stupid."
Post Season -NLCS: In the NLCS against the Houston Astros, he played in all six games. He set an NLCS record for shortstops at the time, in putouts (13), assists (18) and chances (31) in a six-game series. At the plate he was 3-17 batting .176 overall.
Post Season -World Series: In the World Series against the Boston Red Sox, he hit .250 (5-20) scoring three runs & driving in two others.
In Game #5 at Fenway Park he drove in his first run, a 9th inning single off Bruce Hurst in the Mets 4-2 loss. In the bottom of the 7th inning of Game #7, he singled home Lenny Dykstra after Ray Knight had homered off Calvin Schiraldi. He soon scored on Keith Hernandez’s sacrifice fly with the Mets sixth run.
The next season, Santana had the league’s second best fielding% at short (.973) turned over 82 doubles plays & was third in put outs & assists. At the plate he had career best in HRs (5) doubles (21) and RBIs (44), but it was his last season as a Met.
Kevin Elster was on the scene, as the organizations choice for shortstop of the future. On December 11, 1987 Santana was Traded (with minor leaguer Victor Garcia) to the AL New York club for Steve Frey, Phil Lombardi and Darren Reed.
There he played a full season as their regular short stop, 143 games, batting .240 with four HRs and 38 RBIs. He made 22 errors (third among AL short stops) & grounded into 17 double plays.
On an off day in September 1988, Santana chose to visit his old Mets friends at a game at Shea Stadium. That was the night the Mets clinched the NL Eastern Title. The next day he told his AL New York team mates it was his off day & he does what he wants on his days off.
An elbow injury forced him to miss the entire 1989 season, and that November he was released by the Mets.
Mets Career: In his Mets career he played 478 games at short stop, 5th on the Mets all time list. He played 483 games overall, batting 248 with 8 HRs 62 doubles 113 RBIs over four seasons.
In 1990, he signed with the Cleveland Indians joining former 1986 Mets team mates Kieth Hernandez & Jesse Orosco. He would only play in seven games there getting released on April 25th. After a short seven season career he retired at the age of 32.
In his career he batted.246 with 497 hits 13 HRs 74 doubles, five triples, a .295 on base % and 156 RBI in 668 games. On the field he posted a lifetime .969 fielding percentage at short stop (97th all time) making 87 errors & turning 364 double plays.
Retirement: Since his playing career, Santana has been a long time coach in the Dominican Winter League, with the Kansas City Royals, Boston Red Sox & Chicago White Sox farm systems.
He has been with the White Sox since 1998 & is in charge of the White Sox player development in the Dominican Republic.
He is a member of the Mets Alumni Association along with past Mets players, and still makes many personal appearances. He phoned Omar Minaya about a coaching job during the mid 2000's but never got a call back from him.
Santana attended the 1986 Mets, twentieth Anniversary Reunion at She Stadium in 2006 & the closing ceremonies at Shea Stadium in 2008.
Family: He has two sons who are also playing pro baseball.